The intercalated ducts reach the acini. A noticeable peculiarity of the pancreas is that some of the epithelial cells of the intercalated ducts penetrate the centre of most of the acini, partly occluding the lumen. The epithelial cells located in the centre of the acini are called centroacinar cells. In this drawing the centroacinar cells are represented in various planes of section. The glandular acinar cells, pyramidal in shape, have a basal chromophilic cytoplasm and secretory granules at their apex. All acinar cells connect with the narrow central lumen of the acini either directly or indirectly via small intercellular canaliculi.