This animal had its main pancreatic duct ligatured for several weeks. In this experimental condition the digestive enzymes released by the degenerating zymogenic cells led to a complete lysis of the acini. The dispersed islets of Langerhans, which resist lysis, merged into an irregular mass. In this islet tissue, acidophilic A cells (A) can be identified among the pale B cells (B).

Some residual clustered ducts are also visible (*).

Stain: Masson’s Trichrome
Magnification: ×575